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The COVID-19 vaccines provide a high degree of protection against severe disease, hospitalisation, and death. However, no vaccine claimed 100% effectiveness and it is expected that a small proportion of vaccinated individuals may develop a breakthrough infection due to individual differences, virus variants and other factors. We conducted an epidemiological investigation and analysis of an imported case who had finished four doses of vaccination, and in order to provide a relevant reference for regular epidemic prevention and control in the post-pandemic era.
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Background. Since the start of the COVID-19 pandemic, Chad has had 7,417 confirmed cases and 193 deaths, one of the lowest in Africa. Objective. This study assessed SARS-CoV-2 immunity in N'Djamena. Methods. In August-October 2021, eleven N'Djamena hospitals collected outpatient data and samples. IgG antibodies against SARSCoV- 2 nucleocapsid protein were identified using ELISA. "Bambino Gesu" Laboratory, Rome, Italy, performed external quality control with chemiluminescence assay. Results. 25-34-year-old (35.2%) made up the largest age group at 31.9 12.6 years. 56.4% were women, 1.3 women/men. The 7th district had 22.5% and the 1st 22.3%. Housewives and students dominated. Overall seroprevalence was 69.5% (95% CI: 67.7-71.3), females 68.2% (65.8-70.5) and males 71.2% (68.6-73.8). >44-year-old had 73.9% seroprevalence. Under-15s were 57.4% positive. Housewives (70.9%), civil servants (71.5%), and health workers (9.7%) had the highest antibody positivity. N'Djamena's 9th district had 73.1% optimism and the 3rd district had 52.5%. Seroprevalences were highest at Good Samaritan Hospital (75.4%) and National General Referral Hospital (74.7%). Conclusion. Our findings indicate a high circulation of SARS-CoV- 2 in N'Djamena, despite low mortality and morbidity after the first two COVID-19 pandemic waves. This high seroprevalence must be considered in Chad's vaccine policy.
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Objective: Coronaviruses are a large family of viruses that cause different types of diseases. This study aims to evaluate the risk factors for mortality based on comorbidity and sociodemographic characteristics among COVID-19 patients. Methods: This cross-sectional study conducted in Herat, Afghanistan, from February 24 to July 5, 2020, used data provided by the public health department, including sociodemographics, symptoms, comorbidities, hospitalization, contact history, and COVID-19 test type. The Chi-square test was used to observe differences between categorical variables. In bivariate analysis, all independent variables with a significant p-value were put into the model. Odds ratios and 95% confidence intervals were calculated, and a p-value less than 0.05 was considered statistically significant. Results: The study analyzed 11,183 COVID-19 cases, with a 53.5% positivity rate. Recovery rates in the city and Herat province districts were 96.2% and 94.7%, respectively. Case-fatality rates varied with age, with 0.4% for those aged 1-29 and 33% for those aged 80-105. Mortality rates were highest for those with COPD and cancer, at 12.5% and 18.2%, respectively. In the logistic regression results, age, gender, and COPD were significant variables for COVID-19 mortality. Conclusion: By providing more health service facilities to people in risk groups, especially in rural areas, the mortality rate of COVID-19 and other diseases can be decreased.
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Objective: The present study aimed to assess the attitude and perception of Kabul city's residents toward COVID-19 vaccines hesitancy and acceptance. Methods: Applying a cross-sectional study design, the data was collected from 665 participants in Kabul city using a predesigned validated questionnaire. For statistical analysis, Spearman correlation, chi-square, and logistic regression techniques were used. Results: Although the vaccine availability was limited for the public during the survey period, 70.5% of the participants were willing to receive COVID-19 vaccines. Meanwhile, 49.2% participants were concerned about the COVID-19 vaccines side effects. The presence of positive COVID-19 cases among family members and friends (OR: 2.7), presence of fears during COVID-19 pandemic (OR: 4.4) and beliefs that vaccine has important and vital role in people's protection against COVID-19 (OR: 5.3), increase the likelihood of vaccine acceptance among the participants. On the other hand, participant's mistrust of the safety of COVID-19 vaccines (OR: 0.21) and disbelief on ministry of public health "MoPH" advice about COVID-19 vaccine safety and efficiency (OR: 0.27) decrease the odds of COVID-19 vaccine acceptance among the respondents. In addition, a strong correlation was found between vaccine attitude and vaccine acceptance scales (Spearman p=0.52, p<0.001). Conclusion: Although majority of the participants were willing to receive the COVID-19 vaccines, due to high level of participant's concerns about COVID-19 vaccines-related side effects, a great proportion of the respondents were hesitate to receive the COVID-19 vaccines. Accordingly, public awareness about COVID-19 vaccines must be increased to counteract incorrect and misleading propaganda about vaccination and immunization.
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Background: COVID-19's restrictive measures have significantly affected our health, work and social relationships. As yet, less attention has been given to the changes in sex life. Aim: This study investigates people's satisfaction with sex life in Kinshasa in the Democratic Republic of Congo (DRC). Methods: A cross-sectional survey of the general population (18 years and over) was conducted, from 1st to 18th July 2020, in 17 municipalities in Kinshasa and several measures were used: Quality of life MANSA, EQ-5D-3L, UCLA Loneliness;PHQ-9;GAD-7. Prior to conducting data analysis, diagnostic tests for our data were performed to assess distribution, variance and multicollinearity. Descriptive statistics, bivariate correlation and multiple regression analysis were used. Results: Sex life satisfaction increases from young adults aged 18- 35 to those aged 36-55 and then there is a decrease from ages 56-69. After controlling for socio-demographic factors, sex life satisfaction was positively associated with the number and quality of people's friendships (B=0.30, p=0.01) and people's relationships with their families (B=0.32, p=0.03). People who feel lonely have lower sex life satisfaction (B=-0.15, p=0.01). Conclusion: People's quality of their friendships and family relationships are important for their sexual well-being. Healthcare providers and policymakers should consider people's quality of friendships and family relationships when planning to improve the sexual well-being of people in DRC.
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Insights on the indirect effects of the COVID-19 pandemic are critical for designing and implementing policies to alleviate the food security burden it may have caused, and for bolstering rural communities against similar macroeconomic shocks in the future. Yet estimating the causal effects of the pandemic is difficult due to its ubiquitous nature and entanglement with other shocks. In this descriptive study, we combine high-resolution satellite imagery to control for plot-level rainfall with household socio-economic panel data from 2014, 2016, 2019 and 2020, to differentiate the effect of the pandemic from climatic shocks on food security in Morogoro, Tanzania. We find evidence of decreased incomes, increased prices of staple foods, and increased food insecurity in 2020 relative to previous years, and link these changes to the pandemic by asking households about their perceptions of COVID-19. Respondents overwhelmingly attribute economic hardships to the pandemic, with perceived impacts differing by asset level.
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Iron and zinc are important minerals in humans in sub Saharan Africa, whose deficiency is known as "hidden hunger" due to the lack of recognised symptoms in the early stages. Although iron deficiency is the most prevalent, zinc is also involved in inhibition of replication of viruses, including the corona virus (COVID-19). In North Kivu and South Kivu provinces where more than 50% of common bean is produced and consumed in Democratic Republic of Congo, 36% and 47% of preschool children are anemic due to iron deficiency. This paradox is mainly due to insufficiency of iron-rich foods. The aim of this study is to characterise 59 iron and zinc biofortified varieties together with six local varieties of common bean for a potential selection programme in Butembo town in the Democratic Republic of Congo. We focused on 15 qualitative and five quantitative parameters. The qualitative parameters were helpful to distinguish the different morphotypes and for cluster analysis. In addition to the descriptive statistics, the quantitative data were used for Pearson correlation and for principal component analysis, PCA. Qualitative parameters enabled grouping of the study genotypes into 14 morphotypes according to the aspect and colour of the seed coat, the colour around the hilum and the size of seeds. Clustering grouped the 65 genotypes into 12 clusters with the most similar genotypes grouped in the same cluster. Quantitative parameters showed that the study genotypes were dissimilar (P=0.00). A positive correlation was obtained between the days to flowering and the days to maturity (P<0.05) and between the number of pods per plant and the days to flowering. A strong correlation was found between the number of pods per plant and seeds per pod (P<0.01). In contrast, a negative correlation was observed between the 100 seed weight and the number of seeds per pod. The PCA represented on two perpendicular axes showed 64.1% of the total variance of which the 42.3% is explained by the first axis and 21.8% by the second axis. Overall, the study genotypes are morphologically and quantitatively different and thus can be used in a selection programme.
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Background: The COVID-19 pandemic shook the world, claimed a lot of lives, incapacitated many, and forced majority of the world into a lockdown. Vaccination is the key strategy to tackling the virus. Objectives: To ascertain the level of vaccination and the difficulties associated with vaccination, among clinical medical students in Enugu, South-East Nigeria. Materials and Methods: A multistage sampling was used to select 160 respondents while questionnaires (hard and soft copy) were administered to the participants. The IBM Statistical Package for the Social Sciences was used for data entry and data analysis. Results: There was a poor (16.3%) knowledge, negative perception (66.3%), and poor uptake of the COVID-19 vaccine (20.6%). There were statistically significant relationships between vaccination status, knowledge of vaccine, age, and perception of the vaccine (P=0.000) as well as between level of training and vaccine perception (P=0.03). Conclusion: There was very low level of COVID-19 vaccination in the study population that may be attributable to the low knowledge of the vaccine and the high negative perception. The rush to development of the vaccine, possible side effects, and possible long-term complications may be contributory to the poor uptake of the COVID-19 vaccine among the study respondents.
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Income of farming households with low socio-economic status is a task in emerging nations, rural parts of Nigeria inclusive. In connection with this, the entrance of Covid-19 pandemic posed a grave risk to the economy of the households. This study, therefore, investigate the coping strategies in mitigating Covid-19 pandemic's effect on the farming households' income. Data for the paper were collected from 150 farming household heads, through multistage sampling method, with the use of interview scheduled and analysed using appropriate statistics. The findings showed that many (57.3%) of the respondents were male. The widely practiced coping strategies during the pandemic were rationed spending (=2.63), job diversification (=2.40), reduction in hired labour (=2.36), household food rationing (=2.28) among others. There is substantial relationship between household size (r = 0.075, p = 0.003), annual income (r = 0.033, p = 0.004) and coping strategies practiced at p0.005. It was concluded that the pandemic had great effect on the income of the farming household. The study recommends formulation of necessary, effective and urgent policies for assisting and generating fresh employments and revenue producing prospects for affected households.
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Due to various policies measures to curtail the virus, one of which was lockdown, the occurrence of COVID-19 had a negative impact on the nation's economy, especially the rural smallholder farmers. The study looked into how Covid-19 lockdowns affected Nigerian vegetable production. Descriptive statistics, budgetary approaches, multiple regression analysis, and a Likert scale were all used for the analysis. The findings show that most of vegetable growers in the research region were married women (88.33%). About 70% of respondents have completed at least their primary education. The multiple regression analysis results disclosed that number of extensions contact, farm size, market access and transportation cost were significantly affected the level of vegetable production with positive sign while household size had a negative effect on the vegetable production. The findings also showed that after the COVID-19 lockdown, vegetable production was extremely profitable in the study area, with an average gross margin of 82,836.04 that was statistically higher than the 60,709.97 gross margin generated from vegetable production during COVID-19 and the 71,234.91 gross margin generated prior to COVID-19. The constraints faced by vegetable farmers during the covid - 19 restrictions include: high cost of transportation, price fluctuation, and high cost of input, perishability of the produce and lack of improved seeds. It was concluded that Covid 19 pandemic has greater effect on vegetable production in the study areas.
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COVID-19 lockdown, targeted at preventing the spread of coronavirus, had deleterious effects on physical and psychosocial health. This study examined the association between physical activity (PA), sedentary behaviour, health-related quality of life (HRQoL), loneliness and quality of sleep of 507 Nigerian adults during the COVID-19 lockdown. Five hundred and seven respondents (aged 18-67 years) from 12 States completed an online survey on RedCap. Questionnaires comprising the Stages of Change scale, Pittsburgh Sleep Quality Index, International Sedentary Assessment Tool, UCLA Loneliness Questionnaire, Short Form-12 Health Survey, and International Physical Activity Questionnaire were used. Respondents were categorised based on exercise behaviour as non-exercisers, non-regular exercisers, or regular exercisers;and based on age into 18-24, 25-34, 35-44 and > 44 years categories. Descriptive and inferential statistics were used to analyse the data. About 33.1% of respondents did not meet moderate-to-vigorous PA levels. The physical component of HRQoL was positively associated with total PA (p = 0.04). Among the non-exercisers, the odds of being regular exercisers during pre-COVID-19 lockdown were significantly higher for the 35-44 (odds ratio [OR] = 3.49;95% CI = 1.44, 8.48, p = 0.01) and > 44 years age groups (OR = 2.98;95% CI: 1.16, 7.62, p = 0.02) relative to 18-24 years age category. During COVID-19 lockdown, > 44 (OR = 3.65;95% CI: 1.47, 9.07, p = 0.005), 35-44 (OR = 6.42;95% CI 2.75, 14.96, p = 0.001) and 25-34 (OR = 2.35;95% CI: 1.15, 4.80, p = 0.02) years age categories had significant higher odds of being regular exercisers compared to the 18-24 years age group. There was a high rate of physical inactivity among Nigerian adults during the COVID-19 lockdown, which was directly influenced by the physical components of HRQoL. Older age was an independent predictor of exercise behaviour before and during the COVID-19 lockdown among Nigerian adults.
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This study assessed the knowledge and perception of Nigerians about COVID-19 vaccination. A cross-sectional survey was conducted comprising Health and Non-health workers in Nigeria. The knowledge, attitude, and perception of respondents on COVID-19 vaccination in Nigeria was obtained through an online. Logistic regression was employed to determine which factor imparted on COVID-19 vaccination decision. The study showed a significant relationship between COVID-19 vaccination and immigration requirements. The survey showed that 74.07% of the health workers had been vaccinated, while 47.06% of non-Health Workers had been vaccinated. This study recommends that Governments at all levels should create more awareness of the importance of COVID-19 vaccination to increase the number of vaccinated individuals.
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In 2021, the number of children who required PC for STH decreased for pre-SAC from 291.2 million to 260.6 million and for SAC from 732.3 million to 653.7 million (Figure 2). This change was mainly due to revision of the numbers of children who require PC for STH in India, which decreased from 103.5 to 80.7 million for pre-SAC and from 332.1 to 259.1 million for SAC. The decreases were based on impact assessment surveys conducted in the past few years, which changed the endemicity status of some districts. Globally, PC coverage of SAC increased from 47% in 2020 to 62.9% in 2021.The number of SAC reached with deworming increased almost to that before the COVID-19 pandemic (411 million in 2021, 344 million in 2020, 455.9 million in 2019), indicating that countries are recovering.
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Food security is one of the targets of Sustainable Development Goals where it focuses explicitly on food by seeking to end hunger, achieve food security, improved nutrition and promote sustainable agriculture. However, the COVID-19 pandemic lockdown distorted the food system and affected households' capacity to meet its nutritional needs. This study evaluated the effect of COVID-19 pandemic lockdown on households in Jos Metropolis, Plateau State, Nigeria. A multistage sampling technique was used to select 265 households. Data was collected using well-structured questionnaire. The analytical techniques were;Descriptive statistics, FDT Food security index and Z-Statistics Test. The findings indicated that 53% of the household heads were female while 47% were male. The mean age of the respondents was 34 years;the mean Household size was 4 persons. Most of the household heads (68%) were not members of cooperative societies. The result indicated that cereals, legumes/grains, oils/fat, roots and tubers, sugar and honey and meats were the most common food consumed by the households daily before and after the COVID-19 pandemic lockdown. Result of food security status indicated that households consumed an average daily calorie intake of 5860.52 which is higher than the estimate of 1707.88 calorie consumed by the food insecure households. Covid-19 pandemic had effect (p<0.001) on the food security status of households. Food secure households showed higher sensitivity to Covid-19 pandemic compared to 0.807 in food insecure households. The minimum and maximum daily calorie intake of 679.67kcal and 2246.79kcal for food insecure in this study is above the minimum and maximum recommended threshold of 587.58 and 2200 kilocalories for households. The study concludes that the understanding of the effect of the COVID-19 pandemic lockdown on food security status of households is important in developing policy measures such as social safety nets, home feeding program, the school feeding program, conditional cash transfers schemes and improved marketing channels that will help mitigate against households falling into food insecurity during similar pandemic in the future.
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State of the matterDue to the COVID-19 pandemic, and the resulting bottlenecks in the French healthcare system, the management of patients with COVID-19 has been prioritized over that of patients with other pathologies, in particular chronic diseases. The objective of this study was to investigate the impact of COVID-19 on the discovery stage of cancers diagnosed in an organized breast cancer screening program, as well as the impact on the time to supported. Material and methodsAll women aged 50 to 74 for whom cancer has been diagnosed in Cote d'Or as part of the national organized breast cancer screening program (first or second reading) from January 1, 2019 to December 31, 2020 have were included in this study. Using data from pathological anatomy laboratories, clinical centers, and the breast and gynecological cancer registry in Cote d'Or, France, we collected sociodemographic, clinical, and treatment data from all patients. We compared data from the year 2019 (pre-COVID) with that of the year 2020 (COVID). ResultsIn this study, we did not observe any change in the stage of discovery of the cancer at the time of diagnosis, nor any change in the therapeutic strategy. However, we observed a significant increase in infiltrated tumors, a decrease in in situ tumors, and the finding of larger clinical size of in situ tumors after the COVID pandemic. ConclusionWhile these results are reassuring, continued monitoring is needed to determine post-pandemic effects.
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Based on a case study in each country, this study documents the views of Mozambican and Tanzanian smallholders regarding Chinese agricultural investments and the extent to which investors abide by their legitimate land tenure rights as defined by the Voluntary Guidelines for the Responsible Governance of Tenure of Land, Forests and Fisheries in the Context of National Food Security (VGGTs). The VGGTs offer guidelines to government on how to protect the land tenure of rural communities when land is being acquired for large-scale land investments. The study also assessed the impact of the COVID-19 pandemic on smallholders. Due to COVID-19, instead of fieldwork, we conducted telephone interviews with 20 smallholders in Mozambique and 35 in Tanzania. The Mozambican case showed that even when land set aside for investors was not in dispute, smallholders still had unmet expectations, especially regarding investors' corporate social responsibility activities. In the Tanzanian case, even though the land leased by the Chinese investor had been designated as general land, it had laid fallow for a long period, and smallholders had moved back onto the land, only to be displaced in 2017. Although smallholders' views on the investment were mixed, the case underscored the need for government to assess current land use before allocating it to investors - regardless of how the land is classified and especially in areas where land shortages are creating conflict. The cases show that even if communities are consulted about proposed land investments, guidelines need to include clauses that allow for ongoing communications between investors, communities and government officials such that if communities are unsatisfied with the results of the investment, renegotiation is possible. Further, in the event of crises, such as COVID-19, investors should partner with communities and government to limit the extent of harm in communities as a result of the crisis.
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This study analyzed the effects of the COVID-19 pandemic on household income and the determinants of coping strategies in Nigeria, using the combination of the COVID-19 National Longitudinal Phone Survey data and the fourth wave of the General Household Survey, Panel 2018-2019. The fourth wave of General Household Survey, Panel 2018-2019 data is part of the World Bank's Living Standards Measurement Study-Integrated Surveys on Agriculture (LSMS-ISA) and the National Bureau of Statistics of Nigeria collected the data in collaboration with the World Bank and funded by the Federal Government of Nigeria and the Bill and Melinda Gates Foundation. The COVID-19 National Longitudinal Phone Survey 2020, Baseline was implemented by the National Bureau of Statistics in collaboration with the World Bank. The analyses were based on multinomial logistic and multivariate probit models. Multinomial logit regression analysis shows that households that consider the pandemic a substantial threat and households with older heads were more likely to have decreased income while households that received transfer income and self-employed were more likely to have increased income. Several household characteristics exhibited different levels of influence on the choice of coping strategies during the lockdown. Therefore, policy options and support facilities should be developed to foster meaningful (wage/self) employment and coping strategies to achieve optimal results in response to the pandemic.
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This paper assesses the influence of e-commerce service quality on domestic tourists' satisfaction in Tanzania. This was important following closure of international tourism amid COVID-19. A multiple regression analysis to data collected from 150 local tourists in Dar es Salaam assessed influence of variables (reliability of e-services, perceived transaction security, responsiveness of e-services, and e-service ease of use) on customer satisfaction. Findings reveal variables' positive and significant influence statistically at p < 0.05. This implies that domestic tourists' satisfaction through e-commerce service quality in Tanzania is facilitated by reliability of e-services, perceived transaction security, responsiveness of e-services and e-service ease of use. Tourism managers need to ensure that all important pre-requisites necessary for tourism e-service quality provision are in place. The government and other responsible stakeholders need to invest in facilitative digital facilities to ensure optimal e-service quality are reliable at all times.
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This study aimed to evaluate the performance of the PanbioTM Covid-19 Ag Rapid Test (Abbott) in a medical center in Ouagadougou. The PanbioTM COVID-19 Ag test was evaluated from January 26 to March 31, 2021 in symptomatic and asymptomatic patients in the medical Centre of Kossodo. A total of 268 individuals were tested by both SARS-CoV-2 RT-PCR, and antigen RDT. Of these 268 individuals, 52 were positive and 216 were negative for COVID-19 RT-PCR. The performance parameters of the test and its Kappa agreement with the RT-PCR were calculated according to the presence or absence of symptoms in the patients on one hand, and according to the time onset of symptoms on the other hand. The sensitivity of the PanbioTM COVID-19 Ag Rapid Test ranged from 29.63% (95% CI: 13.75 to 50.18) among COVID-19 asymptomatic patients, to 87.5% (95% CI: 52.91 to97.76) among symptomatic patients with symptom onset time of 1-5 days. Similarly, the PanbioTM COVID-19 Ag Rapid Test specificity was 97.3% (95% CI: 90.58 to 99.67) and 96.4% (95% CI: 91.81 to 98.82) in symptomatic and asymptomatic RT PCR negative patients. The PanbioTM COVID-19 Ag Rapid Test shows good performance in detecting COVID-19 cases in patients with a symptom onset time of less than seven (7) days. This performance is even better when the symptom onset is reduced to five (5) days. The results show that the antigen RDT is not suitable for COVID-19 detection among asymptomatic patients.
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The impact of the infamous 2019 pandemic on agriculture has in most cases been generalized. However, the impacts affected sectors and subsectors differently which would advocate different approach to the challenges faced. The main objective of this study is to highlight how the COVID-19 pandemic lockdown affected the activities of the rice farmers, the rice supply chain to find out if the general view of the impact from literatures is similar or different and then propose pro-active measures/strategies to mitigating shocks against any future outbreak. Data were collected from over 300 households which include about 165 rice farmers. All the rice farmers are male, with an average age of 34 years with majority 87% reside in rural areas. Most of the farmers are aware of the existence and dangers of COVID-19. Although there was considerable free movement of rural farmers to access their farms, inputs especially fertilizer has been the major constraints to production. More so, most farmers were only able to sell 1-20% of their paddy rice during the period. Evidence suggest that majority of the rice farmers remain optimistic despite the disruption caused by COVID-19 as over half of the farmers (61%) experienced moderate price of their produce compared to pre-COVID-19 period, 31% were offered higher while only 8% of the farmers reported lower prices. Other interesting finding are highlighted in and proactive recommendations provided against any similar crisis.